Digital Library
Download all 
Poster: Discover the importance of an appropriate linker and the need for thorough product characterization in order to understand the structure-function relationships of an ADC.
Application Note: Evaluate the physical compatibility and extractable results of a proposed single-use solution for conjugation, purification and sterile filtration for ADCs.
White Paper: Explore best practices for ensuring a seamless transition of API raw material supply at critical junctions on the path from preclinical development to commercial manufacturing of small molecule drugs.
White Paper: Discover the most important aspects to consider for lipid-based formulations, strategies in drug development of RNA therapeutics as well as raw material selection.
White Paper: Explore factors to be considered when evaluating and selecting an ODT excipient system suitable for direct compression.
White Paper: Discover the relevant laws and guidelines, as well as voluntary standards developed by the industry to foster implementation.
Poster: Discover our formulation approach to individually adjust the film properties of the respective coating formulations by the addition of different plasticizers.
Poster: Explore our investigations on the effect of excipient combinations to manage protein viscosity.
Webinar Library
Download all 
Learn more about Single Use (SU) processing for ADC GMP manufacturing. Explore our recommendations for consistent transfer of SU processes to manufacturing. Discover the pros and cons of SU for ADCs to understand if SU technology is right for your product. (44:31)
Hear the story of a CMO preparing for the manufacture of a Commercial Antibody Drug Conjugate (ADC). Learn how to properly structure your development work, perform a thorough process risk assessment, prepare for pre-approval inspection. (53:37)
Learn more about the types of PEGs that are used in ADCs and find examples of successful implementation to change the biophysical properties of the construct. Explore why activated PEGs are widely used to improve the pharmacokinetics of drugs. (41:27)
Learn more about the challenges of continuous manufacturing in solid dose, more accurately named “continuous tablet manufacturing”. Find out about the benefits, as well as critical parameters of this new technology and learn how to tackle the latter by choice of excipients. (50:26)
Discover our approach that combines different excipients to reduce viscosity of highly concentrated protein formulations and synergistic effects. Find out why an excipient portfolio approach is useful for reducing viscosity and how excipient combinations can be more efficient than the same concentration of a single excipient, e.g. the leading industry standard. (36:44)
Learn more about the application of RNA therapeutics and the different drug delivery routes used in the clinic. Discover design principles for developing lipids-based RNA formulations and critical parameters to consider for cost effective development and consistent performance of RNA therapeutics and vaccines. (01:08:07)
Discover how the gel-formation properties of PVA introduce sustained release and why compatibility with direct compression leads to simplified formulations. Explore how PVA can provide flexibility in sustained release formulation development. (57:49)
Learn more about the root causes that led to Nitrosamine contaminations in APIs and various potential sources for nitrosamine formation and/or introduction, approach for nitrosamine risk assessment for pharmaceutical starting materials. (1:06:56)
Connect
with an Expert
How can we help you?
Select any of the capabilities below and one of our experts will connect with you.
* Indicates a required field